In 1999, Lara and a guide are exploring the Tomb of Set in search for the Amulet of Horus. Her guide runs away in fear after reading an inscription, leaving Lara to carry on alone. When she finds the sarcophagus of Set, she sees the Amulet sealed on top of a sepulchre, so she pulls it out and leaves. Outsides, she takes a moment to read the Amulet; learning that the Amulet was made by Horus and was used to seal Set in his tomb for eternity and that by removing it, she has set him free. She also discovers that her guide is also working for Von Croy. Lara quickly escapes as a storm brews.
Lara makes her way to Alexandria via train to see Jean Yves again at his office. He tells her that Cleopatra once found the armour and placed it in her palaces to protect it and keep it safe but Von Croy’s men are everywhere, also looking for the armour so she would have to go through the Catacombs to get into Cleopatra’s palaces. She eventually retrieves all five pieces of the armour and returns to Jean Yves only to find that he has been kidnapped by Von Croy, who has left her a ransom note, his life in exchange for the armour.
Lara makes her way to Giza to find the Temple of Horus. During her mission to find the Temple of Horus, she finds all necessary items to summon Horus. She dresses Horus in his battle Armour, puts down the four Holy Scriptures and adds the Amulet to the armour. His spirit starts to return to the statue but Set's spirit is stronger and destroys the armour, stopping Horus. Set takes over the statue and attacks Lara, but she is able to grab the Amulet and escape the temple, using the Amulet to seal this temple and trapping him inside forever. She makes her way out, exhausted as she reaches the exit. In front of her, she sees Von Croy and she asks if he is still possessed by Set. He isn't but he is concerned for her safety but before she can escape, the exit corridor starts to collapse. The floor disappears under her feet and she is left hanging. Von Croy tries to grab her hand but for his own safety, he steps back and the entrance caves in, leaving Lara presumed dead. He bows his head in both respect and sadness.